Scientists have discovered a new way to produce cartilage cells
Weekend warriors know that cartilage injuries in joints like the knees, shoulders and hips are painful and can be debilitating. Conditions that lead to cartilage degeneration like arthritis and temporomandibular disorder (TMJ) affect 350 million people worldwide and cost the U.S. health care system over $303 billion each year. These conditions cause patients to experience increasing pain and discomfort.
A new study by The Forsyth Institute faculty suggests new strategies to make cartilage cells. This could have huge implications for future treatments for cartilage degeneration and injuries. The paper \”GATA3 Mediates Nonclassical B-Catenin Signaling in Skeletal Cell Fate Determination and Ectopic Chondrogenesis\” by Takamitsu maruyama, Daigaku hasegawa and Wei Hsu describes two groundbreaking discoveries, including an understanding of the multifaced protein b catenin.
Dr. Hsu, a Harvard University Professor of Developmental Biology and Senior Scientist at the Forsyth Institute, is also a senior scientist with the Forsyth Insitute. He is an affiliated faculty member at the Harvard Stem Cell Institute. The study was also conducted by Swiss scientists Tomas Valenta, Konrad Basler and Canadian scientists Jody Bouchard and Maxime Bochard. The study is published in the latest issue of Science Advances.
Source:
https://phys.org/news/2022-11-scientists-mechanism-generate-cartilage-cells.html
