A review published in the journal Science and Translational Medicine sheds some light on another mechanism. Researchers explain how neutrophils release toxic substances known as neutrophil extracellular trapped (NETs) in the presence of inflammation. The NETs contain DNA, histones and antimicrobial proteins. They have been shown to cause autoimmune diseases, chronic inflammation diseases and cancer.\n\nThe review emphasizes the role of NETs as a cause of inflammaging. It also highlights the need to understand how NETs regulate and contribute to age-related disease. The authors suggest that targeting NETs could be a viable approach to managing chronic inflammation and age related diseases.