New Method to Halt a-Synuclein Accumulation
Researchers at the Beijing Institute of Brain Disorders discovered a new way to use exosomes in order to deliver aptamers which prevent the accumulation of asynuclein aggregation, the cause of Parkinson’s disease.
a-Synuclein Aggregates
Parkinson’s is also characterized by an aggregation of proteins caused by the loss of proteostasis. This is one of the hallmarks associated with aging. Non-aggregated proteins of a-synuclein are required for the brain’s proper functioning. They facilitate the release dopamine in the nerve cell synapses. A-synuclein is only a problem if proteostasis fails, causing the proteins to misfold, accumulate, and aggregate.
Source:
https://www.leafscience.org/new-method-of-halting-%ce%b1-synuclein-aggregation/
