RNA-binding proteins and Aging
Researchers at Johan Auwerx’s lab at Ecole Polytechnique Federale de Lausanne’s (EPFL) examined the links between RNA-binding protein and aging last month. By binding to mRN, RNA-binding proteins (RBPs), play an important role in post-transcriptional regulation.
Mitochondria
Researchers at EPFL observed increased activity of PUM2 (Pumilio2) when screening for RBPs in aged animals. This can reduce the production of certain proteins. It can do this by binding to specific recognition sites on mRNAs.
Source:
https://www.leafscience.org/rna-binding-proteins-and-aging/