Rapamycin combined with Acarbose extends life span
Increased lifespan of mice by 28-34%. I wonder if side effects would occur as a study found that Rapamycin and Metformin cancelled each other out.
Researchers have published a study in Aging cell that tested several drugs individually and a combination rapamycin + acarbose to see if they can extend the life of genetically heterogeneous mouse strains [1].
The identification of effective anti-aging interventions has been a challenging research problem. Researchers have to contend with the complexity of ageing, as well as the biological heterogeneity within species. They also face reproducibility problems due to different experimental approaches and designs.
In 2004, the National Institute on Aging Interventions Testing Program was launched with these limitations. This is a multi-institutional peer-reviewed study that evaluates potential agents to extend lifespan. The experiments were conducted in parallel by the Jackson Laboratory, the University of Michigan and the University of Texas Health Science Center San Antonio using genetically heterogeneous mouse of both genders.
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