Researchers find a way to slow down aging
Researchers from the University of Minnesota Medical School Paul D. Robbins, Laura J. Niedernhofer, and Mayo Clinic James L. Kirkland, Tamara Tchkonia and Laura J. Obernhofer published a study in Nature Medicine earlier this year that showed it is possible to reduce senescent (damaged) cells and increase lifespan, improve health and prolong life even when treatments are initiated later in life. Fisetin is a natural substance found in fruits and vegetables. They have now shown that treating aged mice with Fisetin has significant benefits for health and longevity.
As we age, our cells become damaged. Cellular senescence is the process that occurs when cells reach a certain degree of damage. Cells also release inflammatory substances that signal the immune system to eliminate damaged cells. The immune system of a younger person is strong and able to remove damaged cells. As people age, the cells are not cleared as efficiently. They begin to build up, causing low-level inflammation and releasing enzymes that degrade tissue.
Robbins, along with other researchers, discovered that a natural substance called Fisetin reduces the amount of damaged cells within the body. This was discovered by treating mice near the end of their lives with this compound. They saw improvements in health and longevity. Fisetin, a senotherapeutic drug that increases lifespan and health, was published recently in EBioMedicine.
Source:
https://medicalxpress.com/news/2018-10-aging.html
