The drug reverses cognitive decline in older people within days
Scientists at UC San Francisco have found that a drug called ISRIB can reverse the age-related declines of memory and mental flexibility. ISRIB has been shown to improve memory function in mice months after a traumatic brain injury, reverse cognitive impairments associated with Down Syndrome, reduce noise-induced hearing loss, combat certain types of prostate carcinoma, and even improve cognition in healthy animal models.
Researchers in the new study published on December 1, 2020 by the open-access journal eLife showed that aged mice quickly regained youthful cognitive abilities, accompanied with a rejuvenation in their brain and immune cells, which could explain the improvement in brain function.
\”ISRIB’s extremely rapid effects demonstrate for the first time that age-related cognitive loss may be caused by an reversible \”blockage\”, rather than a more permanent degradation,\” stated Susanna Rose, Ph.D. Lewis and Ruth Cozen II Chair and Professor in the Departments of Neurological Surgery, Physical Therapy, and Rehabilitation Science.
Source:
https://medicalxpress.com/news/2020-12-drug-reverses-age-related-cognitive-decline.html
