Reprogramming to restore youthful epigenetic information
Circa 2020 Reversing biological clock to reverse aging.
The expression of three Yamanaka transcription factor in retinal ganglion cell in mice restores youthful DNA patterns and promotes axon regrowth after injury. This reverses vision loss both in an aged mouse model and a glaucoma model, suggesting that mammalian tissue retains a record…
Source:
https://www.nature.com/articles/s41586-020-2975-4
