Reverse the Clock: Blood factors restore epigenetic age in rats

Blood Factors Reverse Epigenetic Age

The plasma treatment of old rats resulted in a significant reduction of epigenetic age of blood, heart and liver. These ages were reduced to levels comparable to those of young rats. According to six epigenetic clocks the plasma fraction rejuvenated the liver by 73.4%. The blood by 52.2%. The heart by 52.2%. And the hypothalamus, by 11%. If we use our final epigenetic clocks, the rejuvenation effect is even greater: liver 75%; blood 66%; heart 57%; hypothalamus 11%. According to the final versions of epigenetic clocks the average rejuvenation was 54.2% across four tissues.

Researchers have shown that epigenetic aging can be reduced by half in rats using signals found in their blood.

Epigenetic changes

These epigenetic changes are often referred to as one of the reasons why we age. These changes can damage the basic functions of our cells, increasing the risk of cancer.

Source:

Blood Factors Reverse Epigenetic Age by Half in Rats

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