Reversing Cellular Aging in Mice: Molecules to Restore Telomere length

Researchers identify molecules that reverse the aging of cells

Telomeres, the tiny caps at the ends of chromosomes that protect them from damage and aging, are a central part of a great deal of scientific research on aging. Researchers hope that by intervening with this process they can one day control the process of ageing and its negative health effects. Harvard researchers have discovered a new way forward by discovering a group of small molecules that can restore telomeres in mice.

Telomeres are like the plastic tips at the ends of shoelaces. They prevent DNA from fraying and play a vital role in healthy aging. Each time a cell divides they get a little bit shorter. The sequence continues until the cell is unable to divide anymore and dies.

This process is related to disease and aging, including the rare genetic disorder dyskeratosis (DC). The team concentrated on this condition, which is caused by premature aging of the cells. They hoped to find alternatives to current treatments that involve high-risk bonemarrow transplants with limited benefits.

Source:
https://newatlas.com/medical/reversing-aging-discovery-restore-telomeres/

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