New research shows how to boost muscle regeneration and rebuild tissue
The researchers found that the Yamanaka factor accelerated muscle recovery in mice in the myofiber model by decreasing the levels of Wnt4 protein in the niche. This in turn activated satellite cells.
Salk’s research provides clues to the molecular changes that underlie muscle loss associated with aging.
Loss of muscle mass is one of the effects of aging, and it contributes to disability among older people. Scientists at the Salk Institute study ways to counteract this loss by accelerating the regeneration of muscles tissue using a mixture of molecular substances that are commonly used for stem-cell research.
The researchers showed in a study that was published in Nature Communications on May 25, 2021 that these compounds activated the precursors to muscle cells called myogenic progenitors, which increased the regeneration in mice. The research is still in its early stages and more work will be needed before it can be used on humans. However, this study provides insights into the mechanisms that underlie muscle growth and regeneration. It could also help athletes and older adults to regenerate tissues more effectively.
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New Research Shows How to Boost Muscle Regeneration and Rebuild Tissue
