Scientists Discover Link Between Gut Profiles And Healthy Aging

Shape Your Microbiome Scientists say you’ll live longer if you do.

Barbara Bendlin, from the University of Wisconsin in Madison, wrote: \”This is an interesting study of gut microbiome among older adults.\” While the investigators didn’t look at brain health and cognitive outcomes, they did find that healthy aging is accompanied by gut bacteria that become increasingly unique to each individual starting in middle-age. This type of divergence can also be observed in brain aging. (Full comments below.)

Studies have shown that gut microbiomes undergo rapid changes during the first three to four years of life. This is followed by a period of relative stabilities, and then a second round of change in later years. (Yatsunenko et. al., 2012.; O’Toole & Jeffery, 2015.) Researchers have also discovered that centenarians are less likely to harbor the gut microbes common in healthy, younger people. They live with a microbiota that is becoming increasingly rarefied (Kim et. al., 2018). It is possible that the gut microbiome becomes more personalized with age, but we still don’t know how this affects longevity or aging.

Tomasz Wilmanski, the first author, and his colleagues studied gut microbiomes and other data collected from 9000 individuals aged 18-101 years to find out. These people were from three different cohorts. Arivale was the scientific wellness company founded by Leroy Hood, pioneer of systems biology, and Price. They had enrolled 3653 participants aged 18-87. Arivale offered personalized wellness coaching based on the analysis of data collected from participants’ genomes, other systems and their gut microbiomes. Hood founded the Institute for Systems Biology.

Source:
https://www.alzforum.org/news/research-news/shape-your-microbiome-youll-live-longer-scientists-say-0

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