The chromosome cap’s ability to self-correct can help beat mutations and prevent blood cancer
Mention telomeres.
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People with rare disorders that cause shortened telomeres–protective caps that sit at the end of chromosomes–may be more likely to have blood cancers such as leukemia or myelodyplastic syndrome. Scientists at Johns Hopkins Medicine have now discovered that certain \”self-correcting genetic mutations\” in the bone marrow may protect these patients from cancer.
Researchers suggest that these mutations may also serve as biomarkers to determine if patients who have short telomeres syndromes will develop blood cancers.
Mary Armanios M.D. is the director of the Telomere Center, and a professor of oncology in the Sidney Kimmel Comprehensive Cancer Center of Johns Hopkins. We know that after a certain time, cells with shortened Telomeres can either turn cancerous or remain healthy.
Source:
https://medicalxpress.com/news/2021-09-gene-self-correction-chromosome-caps-mutations.html
