The Neural Basis for Language Impairment among School-Aged Children With Autism Spectrum Disorder

The association between structural brain abnormalities and language impairment among school-aged children with Autism spectrum disorder

The neural basis of language impairment in children with Autism Spectrum disorder (ASD) is not well understood. The present study, which used structural magnetic resonance imaging to compare the volume and surface-based characteristics of the brains of groups of children who have and do not have ASD, also investigated the relationship between these characteristics and the language abilities measured by standardized tools in children with ASD. The study involved 36 school-aged participants: 18 children with ASD, and 18 typically developing controls of similar age and sex. The results showed that there were differences between the groups of children for gray matter volume (volume of gray matter), gray matter thickness (thickness of gray matter), gyrification and cortical complex (fractal dimension).

Source:
https://www.nature.com/articles/s41598-023-28463-w

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