The Non-Invasive Stimulation of Gamma Frequency Brain Rhythms at 40 Hz Reduces Alzheimer’s Pathology in Mouse Models

In mouse models, 40 Hz vibrations reduced Alzheimer’s symptoms and pathology

Multiple research groups have shown that non-invasive stimulation of brain rhythms at 40 Hz, gamma, can reduce Alzheimer’s disease symptoms and pathology in both mice and humans. This has been demonstrated with light and sound. According to MIT researchers, Alzheimer’s mice that were exposed to 40 Hz vibratory stimulation for an hour a night over several weeks had improved motor function and brain health compared to controls.

The MIT group has not been the first to demonstrate that gamma-frequency tactile stimulation can improve brain activity and motor function. However, they are the only ones to show how the stimulation can reduce levels of phosphorylated Tau, the hallmark Alzheimer’s disease protein, as well as keep neurons from dying, or losing their synapse connections, and reduce DNA damage to neural cells.

This work demonstrates a new sensory modality we can use to boost gamma power within the brain,\” said Li Huei Tsai. She is the corresponding author of this study, the director of the Picower Institute for Learning and Memory and Aging Brain Initiative, and Picower professor in the Department of Brain and Cognitive Sciences.

Source:
https://medicalxpress.com/news/2023-05-hz-vibrations-alzheimer-pathology-symptoms.html

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