Meat and Nicotinamide – A Causal Role for Human Evolution, History and Demographics
Circa 2017
The evolution of all animals and humans was heavily influenced by the hunt for meat. Vitamin B3, or nicotinamide, is a key brain-trophic component in meat. As animal predators with ever-larger brains evolved in the Cambrian era, meat and nicotinamide were steadily consumed. The 3-million-year evolutionary process of Homo Sapiens culminated with our demographic success. In light of the meat and nicotinamide consumption, we view human evolution and recent history as well as agricultural and demographic changes. A biochemical and immunological switch is highlighted that affects fertility in the ‘de novo’ tryptophan-to-kynurenine-nicotinamide ‘immune tolerance’ pathway. The nicotinamide-adenine dinucleotide consumption pathways are related to longevity. High meat consumption is associated with moderate fertility and intelligence, with good health and longevity, with a stable population. Low meat/high cereal consumption (shorter than starvation), however, is linked to high fertility and disease. A high meat intake can lead to fertility levels below replacement. Reduced variances in meat intake could help stabilize population growth and improve the human capital.
Keywords: Meat, nicotinamide, evolution, NAD(H), vitamin B3, Malthus, fertility, immunological tolerance, longevity.
We’ll keep going forever, Pa. Because we are the people.
Source:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417583/
