High-throughput screening identifies molecules which reduce cellular stress
Sadly, for many people, growing older means an increased risk of illnesses from cancer to cardiovascular disease. Scientists at the University of Michigan are researching the biological basis of aging in order to develop interventions that may help people lead longer and healthier lives.
In a new article in Science Advances, several promising small molecules are described that reduce cellular stress and may even extend life in mouse skin cell.
David Lombard M.D. Ph.D. is an associate professor in pathology and the lead author of this paper. \”Cellular Stress Resistance appears to be a feature common among long-lived organisms such as mice and invertebrates,\” he says. Lombard is a member of the multidisciplinary team at U-M’s Paul F. Glenn Centre for Aging. Richard Miller, M.D. Ph.D. and his colleague conducted a recent study that found promising drugs to extend the life of mice, including rapamycin (a cancer drug) and acarbose (a diabetes drug).
Source:
https://phys.org/news/2020-10-high-throughput-screening-molecules-cellular.html
