The first hope that ‘Biological Age can be reversed’ comes from a cocktail of drugs
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\”Fahy’s fascination with the thymus goes back to 1986, when he read a study in which scientists transplanted growth-hormone-secreting cells into rats, apparently rejuvenating their immune systems,\” Nature reported. He was surprised to find that no clinical trials had been conducted on this result. He treated himself with DHEA and growth hormone a decade later at the age of 46.
The thymus, located between the lungs & breastbone in the chest, is essential for efficient immunity. Nature reported that \”white blood cells are made in the bone marrow, and mature inside the Thymus where they become T-cells which help the body fight cancer and infections.\” \”But after puberty, the gland shrinks and becomes increasingly clogged with fat. Animal and human studies have shown that growth hormone can stimulate the regeneration of the thymus. But this hormone can also promote diabetes, so the trial included two widely used anti-diabetic drugs, dehydroepiandrosterone (DHEA) and metformin, in the treatment cocktail.\”
In seven out of nine participants, thymus tissue regenerated during the TRIIM study replaced accumulated body fat. Horvath’s task was to analyze the effects of the drugs after the trial on participants’ epigenetic timers.
Source:
https://www.forbes.com/sites/robinseatonjefferson/2019/09/09/cocktail-of-drugs-gives-first-hope-that-biological-age-can-be-reversed/
