Unlocking the Secret of E5 Rejuvenation: The Story of the Oldest Living Lab Rat

How did scientists make this lab rat the oldest rat alive — E5 Rejuvenation?
Talking about E5.

Rats can also be used for research on aging and to cook ratatouille. Take a look at the headline of a recent article. \”We have the longest living female Sprague Dawley rat,\” Dr Harold Katcher said, a former professor of biology at the University of Maryland and now the chief scientific officer of Yuvan Research in California.

So, Rejuvenation & rats. We’re discussing this today. This rat, which has become the longest-living rat of its species, was injected with concentrated plasma from young blood plasma. I’m also examining what this might mean for human therapy. Before we can get to that point, we have to go back in time, to the late 50s and early 60s, when Clive McKay and other researchers, who were performing a procedure known as heterochronic parbiosis, conducted research.

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Conference i mentioned — https://www.curing-aging.com/

TIMESTAMPS:
Intro — 00:00
Plasma & rejuvenation — 00:45
E5 Rat plasma experiments — 04:00
Discussion — 09:44

References:
https://www.theguardian.com/science/2023/feb/08/anti-ageing-…ng-lab-rat.
Patent — https://patentscope.wipo.int/search/en/detail.jsf?docId=WO20…3678-1
Reversing age : dual species measurement with a single clock. Steve Horvath bioRxiv 2020.05.07.082917; doi: https://doi.org/10.1101/2020.05.07.082917
Villeda, S., Plambeck, K., Middeldorp, J. et al. In mice, young blood reverses age related impairments of cognitive function and synapticplasticity. Nat Med 20659-663 (2013). https://doi.org/10.1038/nm.3569
I took the video clips of interviews from @yuvanresearch2749

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